Intraocular pressure: protagonist or supporting actor in glaucoma?

Abstract

Glaucoma, one of the principal causes of visual disability and blindness around the world, is considered a progressive form of optical neuropathy often associated with elevated intraocular pressure (IOP) consequent on abnormal elevated resistance to draining of aqueous humour (AH) through the trabecula (TM) and the Schlemm’s canal. Despite in-depth researches, its aetiology still remains to be clarified. However, all authors agree that the main risk factor on which it is possible to act therapeutically is elevated intraocular pressure (IOP).