A Putative Link Among the Triad: Inflammation, Reprogramming, and Cancer

Abstract

Induced pluripotent stem cells (iPSCs) are generated during ex vivo artificial process, referred to as reprogramming process; on the other hand, reprogramming has been demonstrated to be also involved in human pathological process in vivo, such as metaplastic change. Moreover, a surprising link between reprogramming and inflammation has been revealed. In this Editorial at the triple crossroads, I discuss a novel link among inflammation, reprogramming, and cancer.