Retrospective Analysis of Correlative Factors Affecting Kyphosis Angle Reduction of Osteoporotic Vertebral Compression Fractures with Kyphoplasty

Abstract

AIM: The aim of this retrospective study was to evaluate the correlative factors that affect vertebral kyphotic angle reduction with kyphoplasty. METHODS: This retrospective study was carried out from the Affiliated Hospital of Jiangsu University, Jiangsu, China. One hundred and thirty patients with single-level osteoporotic vertebral compression fracture, undertook kyphoplasty between April 2013 and March 2016 in our institution, were examined and followed to a maximum of one year. An established seven hypothetic independent factors such as; patient variables (Age, Sex), fracture variables (Level, Age and Pre-operative kyphotic angle), and surgical variables (total cement volume, amount of cement leaked) cum kyphotic angle reduction as a dependent variable. Univariate and multivariate linear regression statistic were used to correlate the association between these variables and kyphotic angle reduction. Data processing and analysis were carried out in SPSS 16.0. Results were deemed significant at the 0.05 level (p < 0.05).

RESULTS: Statistical significance occurred in the kyphotic angle immediate postoperative and the final follow-up compared with the preoperative values. Univariate analyses indicated a correlation of kyphotic angle reductions with cement volume used, cement volume leaked and pre-operative kyphotic angle. A final multiple linear regression model indicated a correlation between kyphotic angle reductions with cement volume used and pre-operative kyphotic angle. The conclusive multilinear regression model with all predicted independent variables amounted to a formula that account for 12% of variability in kyphotic angle reduction; pre-operative kyphotic angle (b = 0.195, p = 0.022) and cement volume (b = -0.194, p = 0.024).

CONCLUSION: The preoperative kyphotic angle and cement volume used are the major predictors of kyphotic angle reduction postoperative.