Skull Lesion in Myeloma Mistaken for Myeloma Deposit

Abstract

We report the case of a 85 year old lady with multiple myeloma referred to our specialist spinal unit for treatment of multiple spinal fractures. She had an area of high signal on the occipital region seen on MRI and reported at a peripheral hospital as an erosive skull lesion in the occiput with protrusion of intracranial contents. The site of the erosion would mean that the upper margin of any cervical brace or collar would have potentially impinged on the defect and caused further damage. However on further evaluation at our tertiary myeloma unit the lesion turned out to be a normal variant requiring no further treatment.