Determinants of Non-High Density Lipoprotein-Cholesterol in Bantu Central African Type 2 Diabetic Patients

Abstract

AIM: To define non-HDL-C and to access its relationship with CVD risk factors in Black Bantu Central African T2DM patients with glycemic control. METHODS: This cross-sectional survey was conducted at LOMO MEDICAL Clinic, Kinshasa, capital and megacity of Democratic Republic of the Congo (DRC), between November 1st 2007 and December 30th, 2008. RESULTS: Only LDL-C, TG and dry salted fish were significantly, positively and independently correlated with HD2-among inactive patients. There was an independent, significant and positive correlation between dry salted fish, Systolic blood pressure and Non HDL-C, but an independent significant and Non HDL-C in active participants. In all T2DM patients and adjusted for confounders (intake of beef, HC, TG, LDL-C, ApoB, SBP, HOMA-IR, and intake of fried fats), only regular intake of white refined rice and full milk were the most important, independent and significant determinants of high Non HDL-C ≥135 mg/dL. CONCLUSION: Non-HDL-C may be considered as a marker of inflammation, insulin resistance, hypertension, malnutrition, and atherosclerosis in these Bantu with type 2 diabetes mellitus (T2DM), inappropriate diet, lifestyle changes, and Westernization. Nutritional education and physical activity are recommended in T2DM Central Africans facing health transitions.