MOLECULAR SIGNALLING SAGA IN TUMOUR BIOLOGY

Abstract

‘Cancer’ is a broad term used for malignant tumours that has spread throughout the body. The initiation and progression of tumour is driven by complex signaling pathway that can be majorly categorized as oncogenic signal and anti-oncogenic signal. The development of tumour is regulated by abnormal oncogenic signal. The therapy of tumour is designed via targeting the blockage of oncogenic signal or activation of anti-oncogenic signal. This review is an illustration of different signaling pathway involved in tumour biology and the timeline historical review of progress made in the field of tumour biology.