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Clinical Outcomes of the Phn Intramedullary Nail for Proximal Humeral Fractures

Oscar Ares, Andrea Sallent, Roberto Seijas, Ariadna Caparrós

Oscar Ares, Ariadna Caparrós, Hospital Clinic Barcelona, Spain
Oscar Ares, Oscar Ares, International University of Catalunya, Barcelona, Spain
Andrea Sallent, Vall Hebron Hospital Barcelone, Spain
Roberto Seijas, Orthopedic Surgery, Garcia Cugat Foundation Quiron Hospital Barcelone, Spain
Oscar Ares, Hospital Teknon, Barcelone, Spain

Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http: //creativecommons.org/licenses/by-nc/4.0/

Correspondence to: Roberto Seijas, MD, PhD, Quiron Hospital Barcelona, Pza. Alfonso Comín 5-7, 08035 Barcelone, Spain.
Email: roberto6jas@gmail.com
Telephone: +34932172252
Fax: +34932381634

Received: February 9, 2017
Revised: April 19, 2017
Accepted: April 21 2017
Published online: April 28, 2017

ABSTRACT

AIM: Our aim was to analyze the functional outcomes of our initial experience in the treatment of proximal humeral fractures. The present technique lies in the implantation of an intramedullary nail with a spiral blade and guided interlocking distal bolts.

METHODS: The series consisted of 5 patients (mean age 43.2 years old). Proximal humeral fractures included AO/ASIF type 11-B2 (3 cases) and type 11-A3 (2 cases). Follow-up was 15.7 months, observing absolute bone healing in all cases.

RESULTS: Mean range of motion was 120˚ (SD 12). The mean central score on the Constant scale was 85.60 points (69-100) on the affected side, compared to the 97.60 points (100-88) obtained in the healthy side. The age- and sex-adjusted Constant score was 86.70 (SD 13). The physical component of the SF-12 indicated a moderate impact on health-related quality of life.

CONCLUSION: Based on the favorable clinical and radiological outcome, the PHN nail appears to be an effective implant for attaining stability in displaced fractures, and this should be included as a possible form of treatment within the range of possible surgical repairs.

Key words: PHN intramedullary nail; Proximal humeral fractures; Outcomes; Constant score

© 2017 The Author(s). Published by ACT Publishing Group Ltd. All rights reserved.

Ares O, Sallent A, Seijas R, Caparrós A. Clinical Outcomes of the Phn Intramedullary Nail for Proximal Humeral Fractures. International Journal of Orthopaedics 2017; 4(3): 763-766 Available from: URL: http: //www.ghrnet.org/index.php/ijo/article/view/1987

INTRODUCTION

Proximal humerus fractures, mainly occurring at the surgical neck level, are more common in elderly people whose grade of osteoporosis makes internal synthesis more challenging, being a fall from standing in an elderly osteoporotic woman the most common mechanism of fracture[1,2]. However, the incidence of these fractures is currently increasing in active, young people being a high-energy traumatism the most common cause within this group[3,4,5].

Osteosynthesis of proximal humeral fractures is a source of controversy due to the numerous available treatment options: plates, screws, Kirchner wires, intramedullary nails, percutaneous nailing and external fixation[6,7,8]. Regarding plates and nails, the need to open the affected area and the likely poor bone quality in older patients can make fixation challenging[9,10]. The complications associated to anterograde nails are rotator cuff injury and subacromial syndrome due to proximal migration[11,12], whereas a perforation of the humeral head[13] and supracondylar humeral fracture can occur during retrograde nail placement. Percutaneous fixation with wires can be affected by the musculature of the shoulder, and it is a less stable, technically more difficult osteosynthesis.

Our aim is to describe the clinical and functional outcomes (measured with Constant scale[14], SF-12[15] and DASH questionnaire[16]) of our initial experience in the treatment of proximal humeral fractures using an intramedullary nail with a spiral blade and guided interlocking distal bolts.

Materials and Methods

Five fractures (3 men; 2 women) with a follow-up of 1 year are described. Mean age was 43.2 years old (SD 20.5). The lesion was caused by a high-energy mechanism in 2/5 of cases. Three patients had AO-ASIF type 11-B2 fractures, while the remaining two presenting AO-ASIF type 11-A3. AP and lateral X-rays were used in all cases to diagnose and classify the fracture (Figure 1). Each patient was informed that data concerning the case would be submitted for publication, and signed an informed consent according to it. The hospital’s Ethical Committee approved the present study and this was performed according to the ethical standard laid down in the 1964 Declaration of Helsinki, as revised in 2008.

Proximal humeral nails (PHN) were used in all cases, with a diameter-size of 7 mm and a proximal spiral blade and bolt, as well as two distal interlocking bolts inserted with a single guiding device (Synthes®, Switzerland) (Figure 2). With this system, an oblique bolt can be inserted in a distal-to-proximal direction to increase the stability of the synthesis, if required. All patients underwent immobilization with a sling for two weeks and started physical therapy following this period of time.

Patients were assessed with DASH, SF-12, and Constant tests during the last follow-up (Table 1). On the DASH scale, the lower the score the better the outcome, in contrast to SF-12 and Constant.

Effect size, a standardized difference of means, was calculated to assess the magnitude of the difference in health-related quality of life (HRQoL) scores.

Table 1 Clinical results, measured with three different questionnaires (DASH, SF-12, Constant)
  Follow-up (months)Side FxDominant sideDASHSF-12  Constant AffectedConstant HealthyConstant differenceConstant adjusted (%)
PhysicalMental
Case 118RightRight47.5035.6744.8770881879.5
Case 215LeftRight29.1738.2742.2298100298
Case 314LeftRight056.6857.441001000100
Case 418RightRight35.8336.8056.03691003169
Case 517LeftRight17.5045.0550.6391100991

Figure 1 AP X-rays in neutral position, fracture of the anatomical neck of the humerus (right image; enlarged).

Figure 2 Postoperative X-ray showing the nail with the spiral blade and the three screws.

RESULTS

Consolidation of the fracture without secondary displacement was achieved in all cases.

Mean range of motion was 0-120˚ (SD 12). Mean score on the Constant scale was 85.60 points on the affected side (SD 15.076) and 97.60 points on the healthy side (SD 5.37). Patients presented an average decrease of 12 points (SD 12.75) on the injured side in comparison to the contralateral. The mean weighted score (affected/healthy) for the ability to perform movements with respect to the healthy shoulder was 87.5% (SD 13.08). Patient 4 showed 69 points on the Constant scale due to a subacromial syndrome developed by slight protrusion of the nail. Withdrawal of the implant was proposed to improve the symptoms, but the patient refused this procedure.

Mean score on the DASH scale was 26.00 points (SD 18.15). Mean scores on the SF-12 scale were 42.49 (SD 8.7) for the physical component and 50.24 (SD 6.68) for the mental component. There were no statistically significant differences (p > 0.05) with respect to the age- and sex-adjusted values.

The effect size was obtained as the difference between the means of the group, divided by the standard deviation of the group. Generally accepted guidelines define an effect size around 0.2 as “low”, 0.5 as “moderate” and ≥ 0.8 as “large”[17]. Effect size in the present series showed a moderate worsening for the physical component (0.75) and a small change within the psychological aspect.

DISCUSSION

The major findings of this study were that the radiological and clinical results of our initial experience with the PHN were satisfactory in 100% of our cases. Radiological examination showed correct consolidation in all patients and tests assessing clinical outcomes were highly favorable.

Several studies have shown that confer greater biomechanical stability on the implant rather than simple fixation with screws[18,22]. Hessmann et al. studied the biomechanical properties of four different implants, concluding that both the intramedullary nail and internal fixator were stronger than the plates[18,19]. Furthermore, the system of insertion of a single spiral blade, instead of several screws as in other implants, decreases the risk of neurological lesion[18,20,21]. The highly demanding, young patients in our series achieved complete functional recovery with excellent results. PHN, in contrast to plates and screws, allows a less aggressive approach without the need of opening the focus of fracture or increasing the vascular lesion to the humeral head[23,24].

In patients treated with the 7-mm PHN, no cases of implant breakage during the procedure or follow-up were observed, in line with the outcomes of other studies[25,26]. Moreover, there were no cases of pseudoarthrosis, necrosis of the head or delays in consolidation. The fact that the distal interlocking bolts to block rotation are implanted with the use of a guiding system makes the surgical procedure faster and more highly reproducible. There were no cases of distal blocking failure.

The mean score obtained with the Constant scale[14] compares favorably with the reported scores ranging from 63.0 to 87[18,23,25]. The SF-12 scale did not show relevant differences from general population’s data. Nonetheless, analysis of the impact on HRQoL showed a moderate effect on the physical component, with no effect on the psychological component.

Several limitations should be considered when reviewing the present study. The number of patients included is relatively small, and thus, further randomized studies should be performed to draw clearer conclusions.

This study supports the use of intramedullary nails for selected fractures of the proximal humerus in both young and older patients with osteoporosis. The PHN with spiral blade and guided interlocking distal bolts provides good stability in osteoporotic bones. This technique has less aggressiveness and is particularly useful in fractures at the surgical neck. Despite the fact that it is necessary to invade the rotator cuff, the clinical differences observed between the affected and the healthy sides with the Constant scale were over 80%.

Although the outcomes of PHN (Synthes®) require further assessment, the results obtained in this initial experience were very favorable and promising.

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Peer reviewers: Anestis Iossifidis; Adrianus den Hertog; Ashish Babhulkar

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