Hemodynamic Changes in the Intra-Hepatic Circulation of Hepatosplenic Schistosomiasis: the Role of Hepatic Artery

Abstract

Schistosomal liver disease represents a particular type of chronic liver disease, which presentes unique characteristics that differentiate it from those found in cirrhosis, especially in the vascular bed. Changes in the vascular territory of hepatic artery are still controversial in literature, with some authors advocating no change, while others reporting a greater participation of this sector in hepatosplenic schistosomiasis (HSS). The purpose of this analytical review is to describe the pathophysiology of schistosomal liver disease, with special attention to intra-hepatic vascular alterations regarding the hepatic artery. In conclusion, the literature, to date, has divided opinions in respect to the role of hepatic artery in advanced schistosomal liver disease. We believe this is an interesting field for future research in order to solve the intriguing pathophysiology of hepatic schistosomiasis and use this knowledge for the patients benefit.