Systemic Lupus Erythematosus in a Male Patient With Autoimmune Hepatitis

Abstract

Overlap syndrome involving autoimmune hepatitis (AIH) and systemic lupus erythematosus (SLE) is a rare condition. The difference between the hepatic involvement of SLE and autoimmune hepatitis has not been clearly defined due to the presence of clinical and laboratory common features. We report a 42-year-old male patient with autoimmune hepatitis who presented with intermittent fever, jaundice, and dyspnea. CT scan showed pleural and pericardial effusion, high titer of antinuclear antibodies and positive anti-DNA antibody were found. Our patient fulfilled both the international criteria of SLE and AIH. Clinical symptoms and laboratory findings improved with treatment by corticosteroids.