Oesinophilic Oesophagitis: Current Evidence and Strategies of Management

Abstract

The aim of this study is to review the current evidence of etiology, diagnosis and management of oesinophilic oesophagitis. A review of the PubMed literature (2011-2013) was undertaken. Sixty-five papers were selected based on relevance, power, date of publications and the studies that are reporting adult patients. The exclusion criteria were publications before 2011 and studies that were small or pediatric reports. Majority of the studies were reporting EoE etiology, diagnosis and management. The current evidence is supportive of allergic theory and the management by dietary modification, pharmacology and dilatation for strictures. Distinguishing features from gastro-oesophageal reflux disease were suggested and a prediction system was used to diagnose EoE. EoE is increasingly reported pathology, the etiology of which is an allergic reaction by triggering food or ingested allergens that cascades series of inflammatory responses. Dietary modification, topical steroid and PPI are the main lines of current treatment.