Searching for Gastric Cancer Biomarkers Through Proteomic Approaches

Abstract

Gastric cancer is the fourth most common cancer worldwide and the second leading cause of cancer death. Researchers are increasingly trying to identify molecular biomarkers that can improve gastric cancer diagnosis, be prognostic indicators, or facilitate better decision-making for therapy. High-throughput technologies, or “OMICS”, are particularly interesting biomarker discovery tools. Studies of gastric cancer proteomics are in their infancy, but it is clearly important to discover biomarkers with potential clinical use. The present editorial summarizes the main findings of gastric cancer proteomics and highlights critical points that need to be considered in a study aiming to identify disease biomarkers.