Effects of Aerobic Physical Training in Non-Alcoholic Fat Hepatic Disease Aspects Related to Mitochondrial Biogenesis and Oxidative Stress: A Review

Matheus Santos de Sousa Fernandes, Gabriela Carvalho Jurema Santos, Isael João de Lima, Widemar Ferraz da Silva, Sávio dos Santos Barbosa, Moara Rodrigues Costa, Ravi Marinho dos Santos, Tafnes Laís Pereira Santos de Oliveira, Isabella da Costa Ribeiro, Camila Tenório Calazans


Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of liver disease, affecting about 20% to 30% of the adult population, being found more often in obese individuals (~ 90%). Among the main etiological factors are insulin resistance, mitochondrial dysfunction and oxidative stress. To date, no specific pharmacological treatment for NAFLD, so lifestyle modifications such as: reduction in body weight, diet and regular practice of aerobic physical exercise are effective, however it is not yet elucidated what the main impacts of physical exercise on NAFLD.


Aerobic exercise; Mitochondria and Hepatic Steatosis

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